After updating VUO yesterday, it wouldn't load images. Even though I had answered the Gatekeeper prompt that I wished to use VUO.
Console was whining about the code signing, interestingly.
After closing VUO, then reopening via control+click, and choosing Open from the menu that pops up, everything started working fine. I didn't even get a Gatekeeper prompt the second time opening, so I am unsure why it would make a difference, but it did.
Just a little head's up, if anyone has similar problems.