As a longtime user of QC and building User Interface's to drive QC graphical displays suitable (user friendly) for anyone to use I found QC quite cumbersome. Even with Quartz builder the replication of Input Inspector and resorting to building your own QC buttons, sliders etc was a pain and the results were unimpressive most of the time.
When I started using Mirek's Web-socket plugin it opened a whole new world of web based Custom UIs for QC. It also allows remote operation a possibility from iOS devices etc. Great for a client of mine doing large screen twitter feeds at International sporting events. OSC is the closest current existing tool to do this but it requires using a pre-determined iOS App of some kind and often that's just not what you want to give to your client, just not relevant. Also Websocket has packet security and I've had issues with OSC dropping messages in the past.
HTML/CSS/JS is so quick to build compeling UI/UX with and Vuo/QC are not so I recommend this node to Vuo users to vote for.