As far as I know you need at least High Sierra for eGPU's to work, but much additional work was done in Mojave, so upgrading would probably give the best results.
What Mac are you using? I think the benefits of a eGPU are the highest when you attach an external monitor to the eGPU. Mojave does support eGPU rending on the internal laptop screen, but at a performance penalty (I assume the data has to go back and forth across the PCI-E bus instead of just one way if you hook up a screen to the eGPU box).
I have been thinking and reading about eGPUs for a while now, but haven't taken the plunge...yet...
Looking forward to hear about your experiences with eGPU(s) and Vuo!
I would like to see a MIDI file player similar to the vuo.audio.file.play node so we could play standard MIDI files back. Currently midi input works only in real-time which makes it difficult to export movies based on midi events that are rendered offline.
If we could play back MIDI files, the resulting midi note and controller events could be processed offline while rendering at high resolutions. By connecting the Image Generator protocol time input to the time input of the midi file player, the midi events would be triggered as the frames of the composition are rendered offline.